Product Description
| Cat Number | T21870 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | C 021 dihydrochloride is a potent CCR4 antagonist. C-021 (4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-) dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 nM, respectively. It effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor (IC50: 18 nM). |
| Molecular Weight | 467.65 |
| Purity | 1 |
| Formula | C27H41N5O2 |
| Smiles | N(C=1C2=C(N=C(N1)N3CCC(CC3)N4CCCCC4)C=C(OC)C(OC)=C2)C5CCCCCC5 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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