Product Description
| Cat Number | T22396 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively. |
| Molecular Weight | 372.78 |
| Purity | 0.9912 |
| Formula | C18H14ClFN4O2 |
| Smiles | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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