Product Description
| Cat Number | T2283 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced metastatic cancer. Initial trials correlated doses of Px-12 with increased patient survival. |
| Molecular Weight | 188.31 |
| Purity | 0.996 |
| Formula | C7H12N2S2 |
| Smiles | CCC(C)SSc1ncc[nH]1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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