Product Description
| Cat Number | T23440 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK cells expressing human mGlu4 was 9 nM. TC-N 22A showed very low activity against mGlu 1, 2, 3, 5, and 7 receptors in excitation and forward allosteric models (EC50 >10 μM). TC-N 22A can be used in the study of central nervous system diseases. |
| Molecular Weight | 283.35 |
| Purity | 0.9984 |
| Formula | C14H13N5S |
| Smiles | N(C1=NC=2C=3C(=NNC3)CCCC2S1)C4=CC=CC=N4 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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