Product Description
| Cat Number | T2514 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3). |
| Molecular Weight | 375.4 |
| Purity | 0.9824 |
| Formula | C21H18FN5O |
| Smiles | Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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