Product Description
| Cat Number | T25529 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics[1]. |
| Molecular Weight | 267.35 |
| Purity | 0.9887 |
| Formula | C12H17N3O2S |
| Smiles | CC(C)(C)NC(=S)N\N=C\C1=C(O)C=C(O)C=C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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