Product Description
| Cat Number | T27407 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | GDC0575 monohydrochloride (ARRY575) is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis. |
| Molecular Weight | 414.73 |
| Purity | 0.9785 |
| Formula | C16H21BrClN5O |
| Smiles | O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32.[H]Cl |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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