Product Description
| Cat Number | T28449 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Pradefovir (Remofovir) is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converted to PMEA (9-(2-phosphonylmethoxyethyl)adenine) in human liver microsomes with a K(m) of 60 microM, a maximum rate of metabolism of 228 pmol/min/mg protein, and an intrinsic clearance of about 359 ml/min. |
| Molecular Weight | 423.79 |
| Purity | 0.975 |
| Formula | C17H19ClN5O4P |
| Smiles | C(COCP1(=O)O[C@@H](CCO1)C2=CC(Cl)=CC=C2)N3C=4C(N=C3)=C(N)N=CN4 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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