Product Description
| Cat Number | T28946 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleoside/nucleotide analogs. It effectively inhibits all major HIV-1 and HIV-2 subtypes in fresh human PBMCs, as well as all evaluated HIV-1 strains in monocyte-derived macrophages, displaying EC50 values between 0.2 and 7.2 nM. Oral administration of CMX157 shows no apparent toxicity. Additionally, Tenofovir exalidex exhibits antiviral properties against HBV. |
| Molecular Weight | 569.72 |
| Purity | 0.9954 |
| Formula | C28H52N5O5P |
| Smiles | C([C@H](OCP(OCCCOCCCCCCCCCCCCCCCC)(=O)O)C)N1C=2C(N=C1)=C(N)N=CN2 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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