Product Description
| Cat Number | T29797 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth. |
| Molecular Weight | 290.25 |
| Purity | 0.9711 |
| Formula | C14H11FN2O4 |
| Smiles | OC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(F)c1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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