Product Description
| Cat Number | T31221L |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 HCl does not degrade BRD4 or BRD7 at concentrations up to 5 μM. dBRD9 HCl displays antiproliferative effects in human AML cell lines. |
| Molecular Weight | 856.75 |
| Purity | 0.9937 |
| Formula | C40H47Cl2N7O10 |
| Smiles | O=C1C2=C(C(C3=CC(OC)=C(CN(CC(NCCOCCOCCNC4=CC=CC(C(N5C6C(NC(CC6)=O)=O)=O)=C4C5=O)=O)C)C(OC)=C3)=CN1C)C=CN=C2.Cl.Cl |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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