Product Description
| Cat Number | T3306 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 μM. Inhibits PGE2-induced increases in intracellular cAMP; reverses PGE2-invoked relaxation of mouse trachea (IC50 = 2.7 nM). |
| Molecular Weight | 409.41 |
| Purity | 0.9761 |
| Formula | C23H20FNO5 |
| Smiles | COc1ccc2cc(OCC3(CN(C3)C(=O)c3ccc(F)cc3)C(O)=O)ccc2c1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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