Product Description
| Cat Number | T3312 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes. |
| Molecular Weight | 423.46 |
| Purity | 0.9958 |
| Formula | C22H25N5O4 |
| Smiles | CNC(=O)Nc1cc(Oc2cncc(C)c2)c(cn1)-c1ccc(OCC(C)(C)O)nc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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