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Rg3039

SKU: BTL-TM-B-09777 | Brand: Target Mole
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Product Description

Cat Number T3336
Category Biochemical
Pack Size 1EA
Description Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. RG3039 improves motor function in SMA mice. RG3039 also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models.
Molecular Weight 432.35
Purity 0.9958
Formula C21H23Cl2N5O
Smiles Nc1nc(N)c2c(OCC3CCN(Cc4c(Cl)cccc4Cl)CC3)cccc2n1
Storage -20 ℃
Pdf View Document
Note This product is for Research Use Only
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