Product Description
| Cat Number | T3363 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed. |
| Molecular Weight | 425.6 |
| Purity | 0.996 |
| Formula | C27H39NO3 |
| Smiles | [H][C@@]12NC[C@@H](C)C[C@H]1O[C@]1(CC[C@]3([H])C(C(=O)[C@@]4([H])[C@@]3([H])CC=C3C[C@@H](O)CC[C@]43C)=C1C)[C@@H]2C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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