Product Description
| Cat Number | T3437 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ. Lys05 produced more potent antitumor activity as a single agent both in vitro and in vivo in multiple human cancer cell lines and xenograft models compared with HCQ. Lys05 is therefore a new lysosomal autophagy inhibitor that has potential to be developed further into a drug for cancer and other medical applications. |
| Molecular Weight | 549.75 |
| Purity | 0.9913 |
| Formula | C23H26Cl5N5 |
| Smiles | Cl.Cl.Cl.CN(CCNc1ccnc2cc(Cl)ccc12)CCNc1ccnc2cc(Cl)ccc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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