Product Description
| Cat Number | T3524 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases. |
| Molecular Weight | 495.59 |
| Purity | 0.985 |
| Formula | C16H17BrClN3O3.HBr |
| Smiles | Br.O[C@H]1CCCN[C@@H]1CC(=O)Cn1cnc2cc(Br)c(Cl)cc2c1=O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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