Product Description
| Cat Number | T3528 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel that ameliorates RBC dehydration in the SAD mouse. It blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 = 100 ± 12 nM) and inhibits RBC dehydration with an IC50 of 30 ± 20 nM. Senicapoc is used in the treatment of Sickle Cell Disease and Sickle Cell Anemia. |
| Molecular Weight | 323.34 |
| Purity | 0.995 |
| Formula | C20H15F2NO |
| Smiles | NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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