Product Description
| Cat Number | T35528L |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signaling pathway, resulting in the induction of apoptosis in triple-negative breast cancer (TNBC) cells. Mechanistically, TD52 dihydrochloride disrupts the binding of Elk1 to the CIP2A promoter, effectively reducing CIP2A levels. Notably, TD52 dihydrochloride demonstrates powerful anti-cancer activity while displaying less inhibition of p-EGFR. |
| Molecular Weight | 433.33 |
| Purity | 0.9846 |
| Formula | C24H18Cl2N4 |
| Smiles | C#CC1=CC=CC(NC2=NC3=C(N=C2NC4=CC(C#C)=CC=C4)C=CC=C3)=C1.Cl.Cl |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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