Product Description
| Cat Number | T35841 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | 5-Benzyloxygramine is an N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities. It stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners, resulting in abnormal N protein oligomerization, which was further confirmed in cell studies[1]. [1]. Shan-Meng Lin, et al. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design. J Med Chem. 2020 Mar 26;63(6):3131-3141. |
| Molecular Weight | 280.36 |
| Purity | 0.9633 |
| Formula | C18H20N2O |
| Smiles | CN(C)Cc1c[nH]c2ccc(OCc3ccccc3)cc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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