Product Description
| Cat Number | T3617 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. It specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of the oncometabolite 2-hydroxyglutarate (2 hG), which may induce cellular differentiation and inhibit cellular proliferation in IDH1-expressing tumor cells. |
| Molecular Weight | 582.96 |
| Purity | 0.996 |
| Formula | C28H22ClF3N6O3 |
| Smiles | Fc1cncc(c1)N([C@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)C(=O)[C@@H]1CCC(=O)N1c1cc(ccn1)C#N |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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