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PF-8380

SKU: BTL-TM-B-10364 | Brand: Target Mole
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Product Description

Cat Number T3631
Category Biochemical
Pack Size 1EA
Description PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhibiting autotaxin; reduces LPA levels both in plasma and at the site of inflammation.
Molecular Weight 478.33
Purity 0.9945
Formula C22H21Cl2N3O5
Smiles Clc1cc(Cl)cc(COC(=O)N2CCN(CCC(=O)c3ccc4[nH]c(=O)oc4c3)CC2)c1
Storage -20 ℃
Pdf View Document
Note This product is for Research Use Only
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