Product Description
| Cat Number | T3633 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most tumor cell lines tested. It effectively inhibits mutant Notch receptor activity and, in a xenograft tumor model, inhibits the expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment. |
| Molecular Weight | 464.44 |
| Purity | 0.9736 |
| Formula | C22H23F3N4O4 |
| Smiles | C[C@H](NC(=O)CCC(F)(F)F)C(=O)N[C@H]1c2ccccc2-c2cccnc2N(CCO)C1=O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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