Product Description
| Cat Number | T3636 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | (E)-SIS3 (SIS3), a selective Smad3 inhibitor, can attenuate TGF-β1-dependent Smad3 phosphorylation and DNA binding. It has no effect on p38 MAPK, Smad2, ERK or PI3K signaling. It also inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts and inhibits TGF-β2-induced endothelial cell differentiation in iPSCs. |
| Molecular Weight | 489.99 |
| Purity | 0.9883 |
| Formula | C28H27N3O3·HCl |
| Smiles | Cl.COc1cc2CCN(Cc2cc1OC)C(=O)\C=C\c1c(-c2ccccc2)n(C)c2ncccc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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