Product Description
| Cat Number | T3637 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM). |
| Molecular Weight | 349.29 |
| Purity | 0.9974 |
| Formula | C16H17BrN2S |
| Smiles | Br.Cc1ccc(cc1)-c1cn2c3CCCCc3sc2n1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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