Product Description
| Cat Number | T36527 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 μM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway. |
| Molecular Weight | 321.31 |
| Purity | 0.9826 |
| Formula | C18H12FN3O2 |
| Smiles | Nc1nc(cc(-c2ccc(O)c(O)c2)c1C#N)-c1ccc(F)cc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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