Product Description
| Cat Number | T3691 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | (Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion. |
| Molecular Weight | 358.39 |
| Purity | 0.9834 |
| Formula | C18H22N4O4 |
| Smiles | CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#C[C@@](C)(O)COC |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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