Product Description
| Cat Number | T36935 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of ferroptosis. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free assay, and at a concentration of 61 μM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 μM) reduced cholesterol peroxide-induced MEF death. |
| Molecular Weight | 378.94 |
| Purity | 0.9871 |
| Formula | C14H23ClN4O2S2 |
| Smiles | Cl.NCCNS(=O)(=O)c1ccc(NC(=S)NC2CCCC2)cc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
Share Item: