Product Description
| Cat Number | T3701 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes. MCC950 reduced IL-1β production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE), a disease model of multiple sclerosis. |
| Molecular Weight | 404.48 |
| Purity | 0.983 |
| Formula | C20H24N2O5S |
| Smiles | CC(C)(O)c1coc(c1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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