Product Description
| Cat Number | T3712 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Mivebresib (ABBV-075), also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins. |
| Molecular Weight | 459.47 |
| Purity | 0.9932 |
| Formula | C22H19F2N3O4S |
| Smiles | O(C1=C(C=2C3=C(C(=O)N(C)C2)NC=C3)C=C(NS(CC)(=O)=O)C=C1)C4=C(F)C=C(F)C=C4 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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