Product Description
| Cat Number | T3763 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes. |
| Molecular Weight | 116.07 |
| Purity | 0.9928 |
| Formula | C4H4O4 |
| Smiles | C(=C/C(O)=O)\C(O)=O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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