Product Description
| Cat Number | T38238 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | 2'-Deoxy-2'-fluorocytidine, a nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication and can act synergistically with T705 to enhance the antiviral effects on CCHFV replication[1]. It exhibits antiviral activity with EC50 values of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively, and has a CC50 of >50.0 μM in Huh7 cells[1]. [1]. Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99. |
| Molecular Weight | 245.21 |
| Purity | 0.9903 |
| Formula | C9H12FN3O4 |
| Smiles | Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2F)c(=O)n1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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