Product Description
| Cat Number | T38995 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Taletrectinib free base (AB-106 free base) is a novel potent, selective and orally active ROS1/NTRK inhibitor.Taletrectinib free base has potent inhibitory effects on recombinant ROS1, NTRK1, NTRK2, and NTRK3, with IC50s of 0.207, 0.622, 2.28 and 0.98 nM, respectively, Taletrectinib free base also inhibited ROS1 G2032R and other Crizotinib-resistant ROS1 mutations. |
| Molecular Weight | 405.47 |
| Purity | 0.9987 |
| Formula | C23H24FN5O |
| Smiles | N([C@H](C)C1=CC(F)=CC=C1)C2=NN3C(=CN=C3C=C2)C4=CC=C(OC[C@@H](C)N)C=C4 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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