Product Description
| Cat Number | T4010 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms. |
| Molecular Weight | 174.15 |
| Purity | 0.9873 |
| Formula | C10H6O3 |
| Smiles | Oc1cccc2C(=O)C=CC(=O)c12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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