Product Description
| Cat Number | T4039 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2, 3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. Total cholesterol was reduced by 19% in normolipemic hamsters at a dose of 55 mg/kg/day for 11 days and 25% in hyperlipemic hamsters at a dose of 148 mg/kg/day for 25 days. |
| Molecular Weight | 380.87 |
| Purity | 0.9778 |
| Formula | C22H21ClN2O2 |
| Smiles | Clc1ccc(cc1)C(=O)N1CCC(CC1)=Cc1ccc(cc1)C1=NCCO1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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