Product Description
| Cat Number | T40443 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | JAK2-IN-6, a polysubstituted aminothiazole derivative, is a potent and selective inhibitor of JAK2 (ic50 at 22.86 μg/mL). Jak2-in-6 inhibits the activity of JAK2 enzymes by interfering with Jak2-related signaling pathways, thereby producing therapeutic effects on the specific disease IN which JAK2 is dysregulated, and does not show activity on JAK1 and JAK3. JAK2 is a protein involved in signaling pathways that regulate cell growth and division. Abnormal activation of JAK2 has been linked to a variety of diseases, including some types of cancer and inflammatory diseases. JAK2-IN-6 has antiproliferative activity against cancer cells. |
| Molecular Weight | 335.83 |
| Purity | 0.98 |
| Formula | C14H10ClN3OS2 |
| Smiles | Nc1nc(Nc2ccccc2)sc1C(=O)c1ccc(Cl)s1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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