Product Description
| Cat Number | T4062 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | CAY10602 is a SIRT1 activator derived from high throughput screening for compounds that enhance SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays indicate that CAY10602 dose-dependently suppresses NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells, achieving approximately 75% inhibition at 60 μM without cytotoxicity. |
| Molecular Weight | 418.44 |
| Purity | 0.9887 |
| Formula | C22H15FN4O2S |
| Smiles | Nc1c(c2nc3ccccc3nc2n1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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