Product Description
| Cat Number | T40848 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | NSC 23766 is a Rac1 GTPase inhibitor that inhibits Rac1 activation by targeting guanine nucleotide exchange factors (GEFs), while it has no inhibitory effect on the closely related targets Cdc42 and RhoA, affecting the cell cycle and inhibiting cell proliferation in a dose-dependent manner. It also regulates endothelial NO synthase expression and endothelial function, and inhibits platelet aggregation and γ-secretase activity.NSC23766 competitively inhibits M2 muscarinic acetylcholine receptor (M2 mAChR)-induced Rac1 activation in neonatal rat cardiomyocytes. |
| Molecular Weight | 421.58 |
| Purity | 0.9949 |
| Formula | C24H35N7 |
| Smiles | N=1C(=NC(=CC1NC=2C=CC=3N=C(C=C(N)C3C2)C)C)NC(C)CCCN(CC)CC |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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