Product Description
| Cat Number | T4092 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vivo, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in diverse animal models. AG-126 weakly inhibits epidermal GFRK (IC50: 450 μM) and platelet-derived GFRK (IC50 > 100 μM). |
| Molecular Weight | 215.16 |
| Purity | 0.9872 |
| Formula | C10H5N3O3 |
| Smiles | Oc1cc(C=C(C#N)C#N)ccc1[N+]([O-])=O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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