Product Description
| Cat Number | T4341 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE [2]. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [4]. |
| Molecular Weight | 451.91 |
| Purity | 0.9935 |
| Formula | C23H22ClN5O3 |
| Smiles | COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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