Product Description
| Cat Number | T4382 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite. |
| Molecular Weight | 290.19 |
| Purity | 0.9834 |
| Formula | C11H17Cl2N5 |
| Smiles | Cl.Clc1ccc(NC(=N)NC(=N)NC(C)C)cc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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