Product Description
| Cat Number | T4444 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in the CMGC, CAMK, and TK families [1]. |
| Molecular Weight | 394.9 |
| Purity | 0.9969 |
| Formula | C22H23ClN4O |
| Smiles | CC=1C=2C(=CC=C(C2)C=3C=C(OC[C@H](CC4=CC=CC=C4)N)C=NC3)NN1.Cl |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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