Product Description
| Cat Number | T4567 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). At 10 μM, sulfaphenazole has been shown to inhibit endothelium-derived hyperpolarizing factor synthase, a CYP450 isozyme in the porcine coronary artery homologous to CYP2C8/9 that generates reactive oxygen species in coronary endothelial cells and modulates vascular tone and homeostasis. |
| Molecular Weight | 314.36 |
| Purity | 0.9883 |
| Formula | C15H14N4O2S |
| Smiles | NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=NN1C1=CC=CC=C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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