Product Description
| Cat Number | T4570 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Pipobroman (Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET). Pipobroman allows, within 3 months, to attain a response in more than 90% of patients, without clinically relevant toxicities. The 10-years risk of thrombosis of patients treated with Pipobroman is about 15%, The anti-proliferative activity of Pipobroman on bone marrow megakaryocytes seems of particular value in lowering the occurrence of post-PV and post-ET MMM, whose risk is the lowest registered with available treatments. The 10-year risk of acute leukemia with Pipobroman is 5% in PVand 3% in ET, which is only slightly higher than that expected as a natural evolution of the disease. In conclusion, the use of Pipobroman is a definite alternative to hydroxyurea in patients with PV and ET at high risk of thrombosis. |
| Molecular Weight | 356.05 |
| Purity | 0.9301 |
| Formula | C10H16Br2N2O2 |
| Smiles | BrCCC(=O)N1CCN(CC1)C(=O)CCBr |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
Share Item: