Product Description
| Cat Number | T4672 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 μM) in Cancer Cells.Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K/AKT/mTOR inactivation in colon adenocarcinoma cell CT26.antitumour |
| Molecular Weight | 346.42 |
| Purity | 0.9974 |
| Formula | C20H26O5 |
| Smiles | [H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](OC(=O)C(\C)=C/C)[C@]1([H])[C@H](C)C(=O)O2 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
Share Item: