Product Description
| Cat Number | T4716 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter relationship results from the lability of the direct oxidation product, A'-pyrroline-4-hydroxy-2-carboxylic acid, which loses water spontaneously to form the pyrrole. A similar reaction is catalyzed by the more specific allohydroxy-D-proline oxidase of Pseudomonas. In whole animal observations, pyrrole-2-carboxylate (PCA) ' was identified in rat or human urine after administration of the D-isomers of hydroxyproline, a finding ascribable to the action of D-amino acid oxidase. Urinary excretion of N-(pyrrole-2-carboxyl) glycine has been reported in a 5-year-old affected with type II hyperprolinemia; The child has mild developmental delay, recurrent seizures of the grand mal type and EEG alterations. |
| Molecular Weight | 111.1 |
| Purity | 0.9995 |
| Formula | C5H5NO2 |
| Smiles | OC(=O)C1=CC=CN1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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