Product Description
| Cat Number | T4S0498 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | 1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expression of X-linked inhibitor of apoptosis protein. 3. Glaucocalyxin A inhibits Akt phosphorylation, suppresses proliferation, and promotes apoptosis in a dose-dependent manner, but not in normal glial cells. 4. Glaucocalyxin A inhibits collagen-stimulated tyrosine phosphorylation of Syk, LAT, and phospholipase Cγ2, the signaling events in collagen receptor GPⅥ pathway. 5. Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand. |
| Molecular Weight | 332.43 |
| Purity | 0.9956 |
| Formula | C20H28O4 |
| Smiles | [H][C@@]12CC[C@@H]3[C@@H](O)[C@@]1([C@H](O)C[C@]1([H])C(C)(C)C(=O)CC[C@@]21C)C(=O)C3=C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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