Product Description
| Cat Number | T4S0878 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | 1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. 3. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones. 4. Prunetin significantly suppresses ATP-induced mucin secretion from cultured RTSE cells; Prunetin inhibits the production of MUC5AC mucin protein induced by EGF or PMA from NCI-H292 cells; Prunetin also inhibits the expression of MUC5AC mucin gene induced by EGF or PMA from NCI-H292 cells. |
| Molecular Weight | 284.26 |
| Purity | ≥95% |
| Formula | C16H12O5 |
| Smiles | COc1cc(O)c2c(c1)occ(-c1ccc(O)cc1)c2=O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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