Product Description
| Cat Number | T5122 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding. |
| Molecular Weight | 413.4 |
| Purity | 0.9906 |
| Formula | C19H15N3O6S |
| Smiles | Cc1cc(c(NS(=O)(=O)c2cccc(c2)C(O)=O)cc1-c1cccnc1)[N+]([O-])=O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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