Product Description
| Cat Number | T5622 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Bindarit (AF2838)is an aryl hydrocarbon receptor (AHR) antagonist with IC50 of 39.9 nM in the human glioblastoma U87 cell line. BAY-218 inhibition of AhR stimulates pro-inflammatory monocyte and T cell responses in vitro and drives anti-tumor immune responses, leading to reduced tumor growth in vivo. |
| Molecular Weight | 401.82 |
| Purity | 0.9954 |
| Formula | C20H17ClFN3O3 |
| Smiles | C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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